Dexamethasone corticosteroid APIs from Pfizer CentreOne are found in a variety of therapeutic formulations treating patients every day.
Manufactured in the U.S., Pfizer CentreOne has been reliably synthesizing and supplying commercial volumes of dexamethasone corticosteroid hormone APIs to leading pharma companies for decades.
First synthesized in 1957 and approved for medical use in 1961, dexamethasone is on the World Health Organization's List of Essential Medicines. Available as a generic, dexamethasone is one of the most prescribed medications in the U.S., with nearly 1.5 million prescriptions written by physicians in 20181.
Dexamethasone from Pfizer CentreOne is available in the following chemistries and particle sizes for a broad range of pharmaceutical applications:
For full information on Pfizer CentreOne dexamethasone APIs and related products
| Chemical name Sort descending | CAS# | Compendial | Formula | Molar mass |
|---|---|---|---|---|
| 12-PT | Cas # - 56188-04-6 | Compendial - USP |
Formula -
C15H26O5 |
Molar mass - 286.37 g/mol |
| 16α-hydroxyprednisolone | Cas # - 13951-70-7 | Compendial - US and Canada DMF |
Formula -
C21H28O6 |
Molar mass - 376.45 g/mol |
| 21-(acetyloxy) tetraene (3-TR) | Cas # - 37413-91-5 | Compendial - US DMF |
Formula -
C23H26O4 |
Molar mass - 366.46 g/mol |
| Betamethasone (11-DB) | Cas # - 981-34-0 | Compendial - US DMF |
Formula -
C22H28O5 |
Molar mass - 372.47 g/mol |
| Betamethasone 11 low bromo | Cas # - 981-34-0 | Compendial - US DMF |
Formula -
C22H28O5 |
Molar mass - 372.47 g/mol |
| Dexamethasone acetate anhydrous micronized | Cas # - 1177-87-3 | Compendial - USP, Canada, UK, France and more |
Formula -
C24H33FO7 |
Molar mass - 452.5 g/mol |
| Dexamethasone sodium phosphate | Cas # - 2392-39-4 | Compendial - US, Canada, EP, Singapore |
Formula -
C22H28FNa2O8P |
Molar mass - 516.4 g/mol |
| Dexamethasone USP micronized | Cas # - 50-02-2 | Compendial - USP, EP, JP, Canada and more |
Formula -
C22H29FO5 |
Molar mass - 392.4 g/mol |
| Dexamethasone-8 (8DM) | Cas # - 24916-90-3 | Compendial - US DMF |
Formula -
C22H28O5 |
Molar mass - 372.47 g/mol |
| Diketo acid | Cas # - 1944-63-4 | Compendial - 95-100% |
Formula -
C13H18O4 |
Molar mass - 238.3 g/mol |
| Dinoprost tromethamine | Cas # - 38562-01-5 | Compendial - USP, EP |
Formula -
C20H33O5 |
Molar mass - 475.6 g/mol |
| Enviero™ progesterone micronized | Cas # - 57-83-0 | Compendial - Filed with USFDA and EDQM |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Enviero™ progesterone micronized for soft gel | Cas # - 57-83-0 | Compendial - Filed with USFDA and EDQM |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Enviero™ progesterone USP | Cas # - 57-83-0 | Compendial - Filed with USFDA and EDQM |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Enviero™ progesterone USP special micronized | Cas # - 57-83-0 | Compendial - Filed with USFDA and EDQM |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Epoprostenol sodium | Cas # - 61849-14-7 | Compendial - USP, TGA, EU and more |
Formula -
C20H31NaO5 |
Molar mass - 374.4 g/mol |
| Hydrocortisone acetate, micronized | Cas # - 50-03-3 | Compendial - USP, EP, Canada, JP and more |
Formula -
C23H32O6 |
Molar mass - 404.5 g/mol |
| Hydrocortisone hemisuccinate USP monohydrate | Cas # - 2203-97-6 | Compendial - EP |
Formula -
C25H34O8 |
Molar mass - 462.5 g/mol |
| Hydrocortisone USP | Cas # - 50-23-7 | Compendial - USP, EP, Canada, IP, JP and more |
Formula -
C21H30O5 |
Molar mass - 362.4 g/mol |
| Hydrocortisone USP micronized | Cas # - 50-23-7 | Compendial - USP, EP, Canada, IP, JP and more |
Formula -
C21H30O5 |
Molar mass - 362.4 g/mol |
| Medroxyprogesterone acetate (2-MPB) | Cas # - Mixture | Compendial - Custom |
Formula -
C23H32O4 |
Molar mass - 372.51 g/mol |
| Megestrol acetate USP | Cas # - 595-33-5 | Compendial - USP, EP, Canada |
Formula -
C24H32O4 |
Molar mass - 384.52 g/mol |
| Megestrol acetate USP micronized | Cas # - 595-33-5 | Compendial - USP, EP, Canada |
Formula -
C23H32O4 |
Molar mass - 384.52 g/mol |
| Myristyl-gamma-picolinium chloride | Cas # - 2748-88-1 | Compendial - Custom |
Formula -
C20H36ClN |
Molar mass - 325.97 g/mol |
| Neomycin sulfate 100 mesh | Cas # - 1405-10-3 | Compendial - USP, EP, Canada, IP, JP and more |
Formula -
Mixture |
Molar mass - Mixture |
| Neomycin sulfate micronized | Cas # - 1405-10-3 | Compendial - USP, EP, Canada, IP, JP and more |
Formula -
Mixture |
Molar mass - Mixture |
| Neomycin sulfate USP | Cas # - 1405-10-3 | Compendial - USP, EP, Canada, IP, JP and more |
Formula -
Mixture |
Molar mass - Mixture |
| Nicergoline* | Cas # - 27848-84-6 | Compendial - France, Italy, Poland |
Formula -
C24H26BrN3O3 |
Molar mass - 484.38 g/mol |
| Novobiocin sodium | Cas # - 1476-53-5 | Compendial - USP |
Formula -
C31H35N2NaO11 |
Molar mass - 634.6 g/mol |
| Porcine heparin sodium USP | Cas # - 9005-49-6 | Compendial - USP, Canada |
Formula -
C26H41NO34S4 |
Molar mass - 1134.9 g/mol |
| Prasterone acetate | Cas # - 853-23-6 | Compendial - US DMF |
Formula -
C21H30O3 |
Molar mass - 330.4 g/mol |
| Progesterone micronized for soft gel | Cas # - 57-83-0 | Compendial - US, EP, Canada, IP and more |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Progesterone USP | Cas # - 57-83-0 | Compendial - US, EP, Canada, IP and more |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Progesterone USP micronized | Cas # - 57-83-0 | Compendial - US, EP, Canada, IP and more |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Progesterone wettable powder | Cas # - 57-83-0 | Compendial - USP, EP, Canada, IP, JP and more |
Formula -
C21H30O3 |
Molar mass - 314.4 g/mol |
| Testosterone cypionate | Cas # - 58-20-8 | Compendial - US |
Formula -
C27H40O3 |
Molar mass - 412.6 g/mol |
| Testosterone propionate micronized | Cas # - 57-85-2 | Compendial - US |
Formula -
C22H32O3 |
Molar mass - 344.4 g/mol |
| Testosterone undecanoate | Cas # - 5949-44-0 | Compendial - US, Europe, Canada |
Formula -
C30H48O3 |
Molar mass - 456.7 g/mol |
| Testosterone USP micronized | Cas # - 58-22-0 | Compendial - US, EP, Canada |
Formula -
C19H28O2 |
Molar mass - 288.4 g/mol |
| Testosterone USP micronized | Cas # - 58-22-0 | Compendial - US, Canada, EP |
Formula -
C19H28O2 |
Molar mass - 288.4 g/mol |
| Testosterone USP powder | Cas # - 58-22-0 | Compendial - US, EP, Canada |
Formula -
C19H28O2 |
Molar mass - 288.4 g/mol |
Pfizer CentreOne’s Kalamazoo, Michigan plant has been Pfizer’s center of hormone and steroid manufacturing excellence for decades. In fact, our team produces approximately 1 million kg of API every year at this cGMP certified and fully accredited API manufacturing facility.
We understand the importance of reliable API supply – unpredictable supply is not an option for essential medicine. Our partnerships with customers are based on trust and transparency and we provide strength through our experience.
Our track record is our strongest asset, and this means our customers can count on us for their critical API supply.
When you choose to partner with Pfizer CentreOne, you are purchasing more than API, you are investing in your product’s future. Our team delivers:
Pfizer CentreOne offers a comprehensive range of API compounds and intermediates for drug product developers and manufacturers.
Enviero Progesterone* Heparin Hydrocortisone Progesterone Prostaglandins Steroid Intermediates Testosterone
*Enviero progesterone, the first compound to be launched from Pfizer CentreOne’s green-chemistry program, features no metal catalysts and offers a 70% reduction in carbon footprint versus our traditional processes.
To find out more about Pfizer CentreOne’s APIs and intermediates, as well commercial pricing and supply availability click here.
