Unravelling ADC
complexities with
bio-logic brilliance

As a global CDMO powered by Pfizer, Pfizer CentreOne leverages 20+
years of antibody drug conjugate (ADC) innovation. Backed by a world-class
manufacturing facility in Pearl River, NY, we are ready to help you
get your therapy from clinical to commercialization at speed to answer
patients’ needs.

We harness a strong track record of ADC success, including producing the
world’s first commercially approved ADC product (MylotargTM), to drive
advancement and help us achieve better ADC solutions together.

Speak to our ADC experts today

Expert content

Unravel the complexities of ADC development and manufacturing in our whitepaper.

Download White Paper

Accelerate your ADC development with our end-to-end support, in our brochure.

Download the Brochure

Why choose Pfizer CentreOne to support your antibody drug conjugate innovation?

Experts at the forefront of ADC progression

Experts with advanced degrees and extensive ADC manufacturing experience
A wealth of experience in development and scale-up of antibody and protein technologies
Responsible for the world’s first commercially approved ADC product (Mylotarg^TM)
A track record of outstanding safety performance and on-time delivery

Integrated capabilities

Cytotoxic compounds and drug substance intermediates
Specializing in cytotoxic payloads, linkers and final ADC assembly
Full-process fermentation, recovery, chemical synthesis and purification capabilities
High-value formulations in a wide range of batch sizes
The entire product flow path is single-use

Reliability and quality

Transparent communication enabled through robust protocols for data sharing in real time
Tech transfer and process analytical technology to increase efficiency and help reduce cost
Supply chain reliability to help ensure safe, secure and reliable supply lines
Robust processes developed and optimized to help ensure speed with consistent high quality

Let's collaborate

With decades of experience in taking
molecules from lab to patient, we've learned
invaluable lessons throughout developing and
manufacturing a wide range of sterile injectable
biologic therapeutics, including ADCs.

Discover our biologics development and commercial manufacturing expertise

Antibody drug conjugate excellence from Pearl River

Leveraging approximately 24,000 square feet of ADC manufacturing space specifically designed for highly potent and cytotoxic drug processing, the Pearl River, NY, site is ready to unlock the bio-logical brilliance of your project.

The Pearl River site supports:

Small-scale bacterial fermentation
Recovery
Chemical synthesis
Conjugation reactions
Purification
Formulation
Bulk liquid freezing/thawing

Discover the Pearl River site

How can our pfizer biologics expert help you?

In ADC development and manufacturing, unraveling complexities is key because time is life.
As an experienced global CDMO partner, powered by Pfizer, we can help you skillfully maneuver ADC challenges, keeping pace with scientific advancements and regulatory requirements.

Meet our antibody drug conjugate experts

Dave Merkooloff

Technical Services Site Lead | Pearl River, NY, USA

Responsible for technical transfer and validation of ADCs and immunoconjugates, Dave has over 20 years of experience in commercial and clinical manufacturing to support you throughout your journey.

Lisa Ann Thimmesch

QA director of documentation and training

Lisa Thimmesch has over 20 years of experience supporting Pfizer CentreOne’s customers with regulatory inspection compliance, aseptic and lyophilization manufacturing expertise, quality systems and contract manufacturing quality leadership.

Unravelling ADCcomplexities withbio-logic brilliance